Gli utenti e l'OPAC: indagine sull'utilizzo del catalogo elettronico in una biblioteca pubblica

Questa ricerca mira ad individuare l'utilizzo che l'utenza di un biblioteca pubblica fa del catalogo elettronico, come gli stessi utenti percepiscono le loro capacità e quali strumenti di informazione usano, o quali comportamenti adottano, per reperire ciò di cui hanno bisogno. Si cercherà di capire per quale motivo il catalogo elettronico sembra essere così sottoutilizzato e, proponendo all'utenza un breve corso per impararne l'uso, vedere se sussiste l’interesse a conoscere o imparare ad utilizzare meglio questo strumento

Treatment Options in the Management of Status Epilepticus

Opinion statement: Status epilepticus treatment involves the use of several pharmacologic compounds, which are conceptually divided into three successive and additional lines of action. Because of their rapid onset of action, benzodiazepines represent the first approach; these are followed by classic antiepileptic drugs that are administered intravenously. In refractory episodes, pharmacologic coma induction with an appropriate anesthetic is advocated. Apart from first-line compounds, the level of evidence for medications used in status epilepticus is extremely limited. It is important to specifically address etiology in order to maximize the impact of the antiepileptic therapy. Fine-tuning of the treatment strategy, mainly regarding the choice of whether to induce coma, should be approached by balancing the benefits of rapid control of the status epilepticus with the risks of adverse effects. Although each status epilepticus episode should be treated as rapidly as possible, it appears advisable to reserve coma induction for those forms, such as generalized convulsive status, that have been shown to present a consistent risk of neurologic sequela

No gender differences in egocentric and allocentric environmental transformation after compensating for male advantage by manipulating familiarity

The present study has two-fold aims: to investigate whether gender differences persist even when more time is given to acquire spatial information; to assess the gender effect when the retrieval phase requires recalling the pathway from the same or a different reference perspective (egocentric or allocentric). Specifically, we analyse the performance of men and women while learning a path from a map or by observing an experimenter in a real environment. We then asked them to reproduce the learned path using the same reference system (map learning vs. map retrieval or real environment learning vs. real environment retrieval) or using a different reference system (map learning vs. real environment retrieval or vice versa). The results showed that gender differences were not present in the retrieval phase when women have the necessary time to acquire spatial information. Moreover, using the egocentric coordinates (both in the learning and retrieval phase) proved easier than the other conditions, whereas learning through allocentric coordinates and then retrieving the environmental information using egocentric coordinates proved to be the most difficult. Results showed that by manipulating familiarity, gender differences disappear, or are attenuated in all conditions

A systematic analysis of the XMM-Newton background: III. Impact of the magnetospheric environment

A detailed characterization of the particle induced background is fundamental for many of the scientific objectives of the Athena X-ray telescope, thus an adequate knowledge of the background that will be encountered by Athena is desirable. Current X-ray telescopes have shown that the intensity of the particle induced background can be highly variable. Different regions of the magnetosphere can have very different environmental conditions, which can, in principle, differently affect the particle induced background detected by the instruments. We present results concerning the influence of the magnetospheric environment on the background detected by EPIC instrument onboard XMM-Newton through the estimate of the variation of the in-Field-of-View background excess along the XMM-Newton orbit. An important contribution to the XMM background, which may affect the Athena background as well, comes from soft proton flares. Along with the flaring component a low-intensity component is also present. We find that both show modest variations in the different magnetozones and that the soft proton component shows a strong trend with the distance from Earth.Comment: To appear in Experimental Astronomy. Presented at AHEAD Background Workshop, 28-30 November 2016. Rome, Ital

Bowel Ischemia: A Rare Complication of Thiopental Treatment for Status Epilepticus

Background: Refractory status epilepticus (RSE) treatment is usually performed with comainduction using an appropriate general anesthetic. Most frequent complications are represented by hypotension and infection. Other side-effects may however be encountered. Observations: We describe two patients suffering from acute bowel ischemia after thiopental (THP) treatment for RSE. A 73-year-old man with a complex-patial RSE following an acute stroke received THP (303 mg/kg over 48 h); 36 h after THP discontinuation, he presented abdominal tenderness and lactate elevation. Necrosis of the terminal ileum and colon was seen during surgical exploration; he deceased shortly thereafter. A 21 year-old woman had a cryptogenic de novo generalized-convulsive RSE resistant to 5 attempts of EEG burst-suppression. During the 6th attempt, after THP (840 mg/kg over 150 h) together with mild hypothermia, she developed an ileus with elevated serum lactate; caecum necrosis was observed during surgery. Hypernatremia, acidosis and hyperlactatemia heralded this complication in both patients. Conclusion: In these two patients, mechanical vascular ischemia may have resulted from drug-induced paralytic ileus. To our knowledge, this is the first report describing this potential fatal side effect in adults with RS

A Systematic Analysis of the XMM-Newton Background: I. Dataset and Extraction Procedures

XMM-Newton is the direct precursor of the future ESA ATHENA mission. A study of its particle-induced background provides therefore significant insight for the ATHENA mission design. We make use of about 12 years of data, products from the third XMM-Newton catalog as well as FP7 EXTraS project to avoid celestial sources contamination and to disentangle the different components of the XMM-Newton particle-induced background. Within the ESA R&D AREMBES collaboration, we built new analysis pipelines to study the different components of this background: this covers time behavior as well as spectral and spatial characteristics.Comment: To appear in Experimental Astronomy, presented at AHEAD Background Workshop, 28-30 November 2016, Rome, Italy. 12 pages, 6 figure

Attributed Stream Hypergraphs: temporal modeling of node-attributed high-order interactions

Recent advances in network science have resulted in two distinct research directions aimed at augmenting and enhancing representations for complex networks. The first direction, that of high-order modeling, aims to focus on connectivity between sets of nodes rather than pairs, whereas the second one, that of feature-rich augmentation, incorporates into a network all those elements that are driven by information which is external to the structure, like node properties or the flow of time. This paper proposes a novel toolbox, that of Attributed Stream Hypergraphs (ASHs), unifying both high-order and feature-rich elements for representing, mining, and analyzing complex networks. Applied to social network analysis, ASHs can characterize complex social phenomena along topological, dynamic and attributive elements. Experiments on real-world face-to-face and online social media interactions highlight that ASHs can easily allow for the analyses, among others, of high-order groups' homophily, nodes' homophily with respect to the hyperedges in which nodes participate, and time-respecting paths between hyperedges.Comment: Submitted to "Applied Network Science

Acute seizures in acute ischemic stroke: does thrombolysis have a role to play?

Seizures appear at stroke presentation, during the acute phase or as a late complication of stroke. Thrombolysis has not been investigated as a risk factor despite its potential neurotoxic effect. We try to identify risk factors for seizures during the acute phase of ischemic stroke in a cohort including thrombolysed patients. We undertook a case-control study at a single stroke center using data from Acute Stroke Registry and Analyse of Lausanne (ASTRAL). Patients with seizure occurring during the first 7days following stroke were retrospectively identified. Bi-variable and multivariable statistical analyses were applied to compare cases and randomly selected controls. We identified 28 patients experiencing from seizures in 2,327 acute ischemic strokes (1.2%). All seizures occurred during the first 72h. Cortical involvement, thrombolysis with rt-PA, arterial recanalization, and higher initial NIHSS were statistically associated with seizures in univariated analysis. Backward linear regression identified cortical involvement (OR 7.53, 95% CI 1.6-35.2, p<0.01) and thrombolysis (OR 4.6, 95% CI 1.6-13.4, p=0.01) as being independently associated with seizure occurrence. Overall, 3-month outcome measured by the modified Rankin scale (mRS) was comparable in both groups. In the subgroup of thrombolysed patients, outcome was significantly worse at 3months in the seizure group with 9/12 (75%) patients with mRS ≥3, compared to 6/18 (33.3%) in the seizure-free group (p=0.03). Acute seizures in acute ischemic stroke were relatively infrequent. Cortical involvement and thrombolysis with rt-PA are the principal risk factors. Seizures have a potential negative influence on clinical outcome in thrombolysed patient

Modeling of gain and phase dynamics in quantum dot amplifiers

By means of an electron hole rate equation model we explain the phase dynamics of a quantum dot semiconductor optical amplifier and the appearance of different decay times observed in pump and probe experiments. The ultrafast hole relaxation leads to a first ultrafast recovery of the gain, followed by electron relaxation and, in the nanosecond timescale, radiative and non-radiative recombinations. The phase dynamics is slower and is affected by thermal redistribution of carriers within the dot. We explain the ultrafast response of quantum dot amplifiers as an effect of hole escape and recombination without the need to assume Auger processe